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Abstract Sleep loss has been shown to alter risk preference during decision-making. However, research in this area has largely focussed on the effects of total sleep deprivation (TSD), while evidence on the effects of sleep restriction (SR) or the potentially moderating role of sex on risk preference remains scarce and unclear. The present study investigated risky decision-making in 47 healthy young adults who were assigned to either of two counterbalanced protocols: well-rested (WR) and TSD, or WR and SR. Participants were assessed on the Lottery Choice Task (LCT), which requires a series of choices between two risky gambles with varying risk levels. Analyses on the pooled dataset indicated across all sleep conditions, participants were generally more risk-seeking when trying to minimise financial loss (LOSSES) than while trying to maximise financial gain (GAINS). On GAINS trials, female participants were more risk-averse during TSD and SR, whereas male participants remained unchanged. On LOSSES trials, female participants remained unchanged during TSD and SR, whereas male participants became more risk-seeking during TSD. Our findings suggest the relationship between sleep loss and risk preference is moderated by sex, whereby changes in risk preference after TSD or SR differ in men and women depending on whether the decision is framed in terms of gains or losses. 

The confirmation bias, unlike other decision biases, has been shown both empirically and in theory to be enhanced with deliberation. This suggests that limited attention, reduced deliberation, or limited available cognitive resources may moderate this bias. We aimed to test this hypothesis using a validated confirmation bias task in conjunction with a protocol that randomly assigned individuals to one week of at-home sleep restriction (SR) or well-rested (WR) sleep levels. We also used a measure of cognitive reflection as an additional proxy for deliberation in our analysis. We tested the hypotheses that the confirmation bias would be stronger for WR participants and those higher in cognitive reflection on a sample of 197 young adults. Our results replicated previous findings, and both males and females separately displayed the confirmation bias. Regarding our deliberation hypotheses, the confirmation bias results were most precisely estimated for those having thought relatively more about the issue of gun control. Additionally, for the subset of individuals having thought relatively more about gun control, we found evidence that the confirmation bias was stronger for those higher in cognitive reflection and, somewhat less robustly, for those participants who were (objectively) well-rested.